| 名稱 | PMS2 p.D60E Reference Standard 標(biāo)準(zhǔn)品 |
| 型號 | CBP10578 |
| 報(bào)價(jià) | 900 |
| 特點(diǎn) | PMS2 p.D60E Reference Standard |
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Email： zhangxiangwen@cobioer.com
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基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10578PMS2 p.D60E Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
CBP10578 | |
| Format | Genomic DNA |
| Description | PMS2, PMS1 homolog 2, mismatch repair system component, interacts with MLH1 to form the MutL-alpha complex, which functions in DNA mismatch repair and is associated with microsatellite instability (MSI) and genomic stability. Germline PMS2 mutations are associated with Lynch syndrome , mutations in PMS2 are associated with susceptibility to colon cancer and endometrial cancer, and overexpression has been reported in prostate cancer. |
| Technical Data | |
| DNA Change | c.180C>A |
| AA Change | p.D60E |
| Mutation type | Missense _Mutation |
| Zygosity | Heterozygous |
| Allelic Frequency | 25% |
| Transcript | NM_000535.7 |
| Cosmic ID | COSM3084744 |
| Chr position(GRCh37) | chr7:6043673 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
